

| Numéro de catalogue | HP896014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KCNE4 Polyclonal Antibody (HP896014) is a rabbit polyclonal antibody detecting KCNE4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human KCNE4 (His2-Glu86). | ||||||||
| Cible | Minimum potassium ion channel-related peptide 3, Potassium voltage-gated channel subfamily E member 4, KCNE4, Potassium channel subunit beta MiRP3, MinK-related peptide 3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8WWG9 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Potassium voltage-gated channel subfamily E member 4 (KCNE4) is a ~23 kDa protein. Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. 1. Grunnet, M. et al. (2002) The Journal of physiology 542, 119-30. PMID: 12096056 2. Vanoye, CG. et al. (2009) The Journal of general physiology 134, 207-17. PMID: 19687231 3. Roura-Ferrer, M. et al. (2010) Journal of cellular physiology 225, 692-700. PMID: 20533308 4. Abbott, GW. (2016) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30, 2959-69. PMID: 27162025 | ||||||||
| Note | For research use only. |
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