Human KCNE4 Recombinant Protein (N-GST & C-His) (HP896022)

Name: Human KCNE4 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HP896022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP896022
Description	Recombinant Human KCNE4 Protein, N-GST & C-His (HP896022) expressed in E. coli, spanning His2-Glu86. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q8WWG9
Protein length	His2-Glu86
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	36.84 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	KCNE4, MiRP3, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3, Potassium voltage-gated channel subfamily E member 4
Background	Potassium voltage-gated channel subfamily E member 4 is a ~23 kDa protein. Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. 1. Grunnet, M. et al. (2002) The Journal of physiology 542, 119-30. PMID: 12096056 2. Vanoye, CG. et al. (2009) The Journal of general physiology 134, 207-17. PMID: 19687231 3. Roura-Ferrer, M. et al. (2010) Journal of cellular physiology 225, 692-700. PMID: 20533308 4. Abbott, GW. (2016) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30, 2959-69. PMID: 27162025
Note	For research use only

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Datasheet

Human KCNE4 Recombinant Protein (N-GST & C-His).pdf

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Human KCNE4 Recombinant Protein (N-GST & C-His) (HP896022)

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