Anti-Human KRAS/K-Ras 2 Recombinant Antibody (SAA1513) (HF904013)

Name: Anti-Human KRAS/K-Ras 2 Recombinant Antibody (SAA1513)
Brand: abinScience
SKU: HF904013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF904013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1513

Objetivo

c-Ki-ras, RASK2, GTPase KRas, K-Ras 2, c-K-ras, KRAS, Ki-Ras, KRAS2

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P01116

RRID

Anti-Human KRAS/K-Ras 2 Antibody (SAA1513) (abinScience Cat# HF904013, RRID:AB_3727274)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

GTPase KRas (K-Ras 2) is a ~21 kDa protein. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Activates MAPK1/MAPK3 resulting in phosphorylation and ultimately degradation of GJA1. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.

1. Gremer, L. et al. (2011) Human mutation 32, 33-43. PMID: 20949621

2. Bernal Astrain, G. et al. (2025) Nature communications 16, 647. PMID: 39809765

3. Yang, MH. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10843-8. PMID: 22711838

4. Zimmermann, G. et al. (2013) Nature 497, 638-42. PMID: 23698361

5. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human KRAS/K-Ras 2 Antibody (SAA1513)

Referencias

Datasheet

Anti-Human KRAS/K-Ras 2 Recombinant Antibody (SAA1513).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo