Anti-Human KRAS Recombinant Nanobody (SBT-100) (HF904023)

Name: Anti-Human KRAS Recombinant Nanobody (SBT-100)
Brand: abinScience
SKU: HF904023
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF904023

Descripción

Anti-Human KRAS Nanobody (SBT-100) [SBT-100] (HF904023) is a alpaca monoclonal antibody detecting KRAS in ELISA, IF. Suitable for Human.

Reactividad de especies

Human

Aplicaciones

ELISA, IF

Especie huésped

Alpaca

Clonalidad

Monoclonal

Isotipo

VHH-His

ID de clon

SBT-100

Objetivo

EC:3.6.5.2, GTPase KRas, GTPase KRas, N-terminally processed, K-Ras 2, KRAS, KRAS2, Ki-Ras, RASK2, c-K-ras, c-Ki-ras

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column.

Número de acceso

P01116

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

GTPase KRas is a ~21 kDa protein. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Activates MAPK1/MAPK3 resulting in phosphorylation and ultimately degradation of GJA1. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.

1. Gremer, L. et al. (2011) Human mutation 32, 33-43. PMID: 20949621

2. Bernal Astrain, G. et al. (2025) Nature communications 16, 647. PMID: 39809765

3. Yang, MH. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10843-8. PMID: 22711838

4. Zimmermann, G. et al. (2013) Nature 497, 638-42. PMID: 23698361

5. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human KRAS Recombinant Nanobody (SBT-100).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo