

| Número de catálogo | HV505014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human LAMP3 Polyclonal Antibody (HV505014) is a rabbit polyclonal antibody detecting Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human LAMP3 (Ser222-Cys376). | ||||||||
| Objetivo | Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9UQV4 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Lysosome-associated membrane glycoprotein 3 (LAMP3) is a ~44 kDa protein. Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. 1. Dominguez-Bautista, JA. et al. (2015) European journal of cell biology 94, 148-61. PMID: 25681212 2. Nagelkerke, A. et al. (2014) Endocrine-related cancer 21, 101-12. PMID: 24434718 3. Liao, X. et al. (2018) Molecular and cellular endocrinology 470, 160-167. PMID: 29056532 4. de Saint-Vis, B. et al. (1998) Immunity 9, 325-36. PMID: 9768752 | ||||||||
| Nota | For research use only |
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