Human LAMP3 Recombinant Protein (N-His) (HV505012)

Name: Human LAMP3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HV505012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HV505012
Description	Recombinant Human LAMP3 Protein, N-His (HV505012) expressed in E. coli, spanning Ser222-Cys376. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9UQV4
Protein length	Ser222-Cys376
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.57 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403
Background	Lysosome-associated membrane glycoprotein 3 is a ~44 kDa protein. Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. 1. Dominguez-Bautista, JA. et al. (2015) European journal of cell biology 94, 148-61. PMID: 25681212 2. Nagelkerke, A. et al. (2014) Endocrine-related cancer 21, 101-12. PMID: 24434718 3. Liao, X. et al. (2018) Molecular and cellular endocrinology 470, 160-167. PMID: 29056532 4. de Saint-Vis, B. et al. (1998) Immunity 9, 325-36. PMID: 9768752
Note	For research use only

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SDS-PAGE

SDS-PAGE for Recombinant Human LAMP3 Protein, N-His

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Datasheet

Human LAMP3 Recombinant Protein (N-His).pdf

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Human LAMP3 Recombinant Protein (N-His) (HV505012)

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