Anti-Human LAMP3 Polyclonal Antibody (HV505014)

Name: Anti-Human LAMP3 Polyclonal Antibody
Brand: abinScience
SKU: HV505014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV505014

Description

Anti-Human LAMP3 Polyclonal Antibody (HV505014) is a rabbit polyclonal antibody detecting Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant human LAMP3 (Ser222-Cys376).

Target

Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q9UQV4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Lysosome-associated membrane glycoprotein 3 (LAMP3) is a ~44 kDa protein. Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity.

1. Dominguez-Bautista, JA. et al. (2015) European journal of cell biology 94, 148-61. PMID: 25681212

2. Nagelkerke, A. et al. (2014) Endocrine-related cancer 21, 101-12. PMID: 24434718

3. Liao, X. et al. (2018) Molecular and cellular endocrinology 470, 160-167. PMID: 29056532

4. de Saint-Vis, B. et al. (1998) Immunity 9, 325-36. PMID: 9768752

Note

For research use only

Images

References

Datasheet

Anti-Human LAMP3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-Human LAMP3 Polyclonal Antibody (HV505014)

Overview

Images

References

Datasheet

SDS

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