Anti-Human LGR4/GPR48 Recombinant Antibody (SAA2706) (HV980207)

Name: Anti-Human LGR4/GPR48 Recombinant Antibody (SAA2706)
Brand: abinScience
SKU: HV980207
Price: 191 USD
Availability: InStock

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Обзор

Каталожный номер	HV980207
Реактивность видов	Human
Применения	ELISA, FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	SAA2706
Цель	G-protein coupled receptor 48, GPR48, LGR4, Leucine-rich repeat-containing G-protein coupled receptor 4
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q9BXB1
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4/GPR48) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.
Примечание	For research use only

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Anti-Human LGR4/GPR48 Recombinant Antibody (SAA2706).pdf

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Formula

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