Anti-Human LGR4 Recombinant Antibody (SAA0107) (HV980107)

Name: Anti-Human LGR4 Recombinant Antibody (SAA0107)
Brand: abinScience
SKU: HV980107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV980107
Species reactivity	Human
Applications	ELISA, FCM, IHC, WB
Host species	Human
Isotype	IgG1
Clone ID	SAA0107
Clonality	Monoclonal
Target	GPR48, Leucine-rich repeat-containing G-protein coupled receptor 4, LGR4, G-protein coupled receptor 48, RHJ50601
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9BXB1
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human LGR4 Antibody (ABS0206).

References

Datasheet

Anti-Human LGR4 Recombinant Antibody (SAA0107).pdf

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Anti-Human LGR4 Recombinant Antibody (SAA0107) (HV980107)

Overview

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Datasheet

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