

| Каталожный номер | HV980013 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-Human LGR4 Nanobody (SAA2294) [SAA2294] (HV980013) is a alpaca monoclonal antibody detecting LGR4 in ELISA. Suitable for Human.
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| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Alpaca | ||||
| Клоональность | Monoclonal | ||||
| Изотип | VHH-His | ||||
| ID клона | SAA2294 | ||||
| Цель | Leucine-rich repeat-containing G-protein coupled receptor 4, G-protein coupled receptor 48, LGR4 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Purified by Nickel column. | ||||
| Номер доступа | Q9BXB1 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo. | ||||
| Примечание | For research use only |

SDS-PAGE for Anti-Human LGR4 Nanobody (SAA2294)




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