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Anti-Human LGR4 Recombinant Nanobody (SAA2295) (HV980023)

Anti-Human LGR4 Recombinant Nanobody (SAA2295)
Anti-Human LGR4 Recombinant Nanobody (SAA2295)
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Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHV980023
Descripción
Anti-Human LGR4 Nanobody (SAA2295) [SAA2295] (HV980023) is a alpaca monoclonal antibody detecting LGR4 in ELISA. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedAlpaca
ClonalidadMonoclonal
IsotipoVHH-His
ID de clonSAA2295
Objetivo G-protein coupled receptor 48, GPR48, LGR4, Leucine-rich repeat-containing G-protein coupled receptor 4
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by Nickel column.
Número de acceso Q9BXB1
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.

Nota For research use only
Imágenes
  • Anti-Human LGR4 Recombinant Nanobody (SAA2295)

    SDS-PAGE

    SDS-PAGE for Anti-Human LGR4 Nanobody (SAA2295)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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