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Anti-Human LGR4 Recombinant Nanobody (SAA2295) (HV980023)

Anti-Human LGR4 Recombinant Nanobody (SAA2295)
Anti-Human LGR4 Recombinant Nanobody (SAA2295)
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  • 50ug
  • 100ug
  • 1mg
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Aperçu
Numéro de catalogueHV980023
Description
Anti-Human LGR4 Nanobody (SAA2295) [SAA2295] (HV980023) is a alpaca monoclonal antibody detecting LGR4 in ELISA. Suitable for Human.
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteAlpaca
ClonalitéMonoclonal
IsotypeVHH-His
ID de cloneSAA2295
Cible G-protein coupled receptor 48, GPR48, LGR4, Leucine-rich repeat-containing G-protein coupled receptor 4
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Purified by Nickel column.
Numéro d'accès Q9BXB1
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.

Note For research use only
Images
  • Anti-Human LGR4 Recombinant Nanobody (SAA2295)

    SDS-PAGE

    SDS-PAGE for Anti-Human LGR4 Nanobody (SAA2295)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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