Anti-Human LINGO1 Recombinant Antibody (SAA0824) (HV367107)

Name: Anti-Human LINGO1 Recombinant Antibody (SAA0824)
Brand: abinScience
SKU: HV367107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HV367107
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	SAA0824
Objetivo	LRRN6A, LERN1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, LINGO1, Leucine-rich repeat neuronal protein 6A, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q96FE5
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO1) is a ~69 kDa protein. Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 1. Mi, S. et al. (2004) Nature neuroscience 7, 221-8. PMID: 14966521 2. Park, JB. et al. (2005) Neuron 45, 345-51. PMID: 15694321 3. Mi, S. et al. (2005) Nature neuroscience 8, 745-51. PMID: 15895088
Nota	For research use only.

Imágenes

Flow Cytometry

Flow-cytometry using anti-human LINGO1 antibody.LINGO1 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human LINGO1 antibody monoclonal antibody (Catalog # HV367107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

Referencias

Datasheet

Anti-Human LINGO1 Recombinant Antibody (SAA0824).pdf

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Formula

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