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| カタログ番号 | HY234014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human LIPC Polyclonal Antibody (HY234014) is a rabbit polyclonal antibody detecting LIPC in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LIPC (Glu47-Pro478). | ||||||||
| ターゲット | Phospholipase A1, Lipase member C, LIPC, Hepatic lipase, Hepatic triacylglycerol lipase, Lysophospholipase, HTGL, HL | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11150 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Hepatic triacylglycerol lipase (LIPC) is a ~55 kDa protein. Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles. Also exhibits lysophospholipase activity. Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates. In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position. 1. McCoy, MG. et al. (2002) Journal of lipid research 43, 921-9. PMID: 12032167 2. Yang, P. et al. (2015) Biochimica et biophysica acta 1851, 1327-36. PMID: 26193433 3. Dugi, KA. et al. (1995) The Journal of biological chemistry 270, 25396-401. PMID: 7592706 4. Hill, JS. et al. (1996) The Journal of biological chemistry 271, 22931-6. PMID: 8798474 | ||||||||
| 注意事項 | For research use only. |
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