Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Monoclonal Antibody (1A357) (HC293015)

Name: Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Monoclonal Antibody (1A357)
Brand: abinScience
SKU: HC293015
Price: 194 USD
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Número de catálogo	HC293015
Descripción	Anti-Human Lp-PLA2/PAF-AH Monoclonal Antibody (1A357) [1A357] (HC293015) is a mouse monoclonal antibody detecting PAF acetylhydrolase in ELISA, IFA, TIA. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Reactividad de especies	Human
Aplicaciones	ELISA, IFA, TIA
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	1A357
Inmunógeno	Human Lp-PLA2/PAF-AH Protein.
Objetivo	Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 3.1.1.47, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA(2), PAF 2-acylhydrolase, PLA2G7, PAFAH
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q13093
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Platelet-activating factor acetylhydrolase (Lp-PLA2/PLA2G7) is a ~50 kDa protein. Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response. At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position. Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells. 1. Stafforini, DM. et al. (1999) The Journal of biological chemistry 274, 7018-24. PMID: 10066756 2. Stafforini, DM. et al. (2006) The Journal of biological chemistry 281, 4616-23. PMID: 16371369 3. Kriska, T. et al. (2007) The Journal of biological chemistry 282, 100-8. PMID: 17090529 4. Stremler, KE. et al. (1991) The Journal of biological chemistry 266, 11095-103. PMID: 2040620 5. Tjoelker, LW. et al. (1995) Nature 374, 549-53. PMID: 7700381 6. Tew, DG. et al. (1996) Arteriosclerosis, thrombosis, and vascular biology 16, 591-9. PMID: 8624782 7. Min, JH. et al. (1999) Biochemistry 38, 12935-42. PMID: 10504265 9. Gardner, AA. et al. (2008) The Journal of biological chemistry 283, 17099-106. PMID: 18434304
Nota	For research use only.

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Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Monoclonal Antibody (1A357).pdf

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Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Monoclonal Antibody (1A357) (HC293015)

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