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| カタログ番号 | HY363117 |
|---|---|
| ブランド | abinScience |
| 種反応性 | Human, Mouse, Rat, Bovine |
| アプリケーション | ELISA, FCM, IF(P), WB |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a |
| クローンID | 5D2 |
| 抱合 | FITC |
| ターゲット | Phospholipase A1, LIPD, Lipoprotein lipase, LPL |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC |
| アクセッション番号 | P06858 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Lipoprotein lipase (LPL/LIPD) is a ~53 kDa protein. Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. 1. Lutz, EP. et al. (2001) The Journal of clinical investigation 107, 1183-92. PMID: 11342582 2. Pingitore, P. et al. (2016) Journal of clinical lipidology 10, 816-823. PMID: 27578112 3. Weinstock, PH. et al. (1995) The Journal of clinical investigation 96, 2555-68. PMID: 8675619 4. McCoy, MG. et al. (2002) Journal of lipid research 43, 921-9. PMID: 12032167 5. Dugi, KA. et al. (1995) The Journal of biological chemistry 270, 25396-401. PMID: 7592706 6. Goulbourne, CN. et al. (2014) Cell metabolism 19, 849-60. PMID: 24726386 7. Allan, CM. et al. (2017) Journal of lipid research 58, 216-225. PMID: 27811232 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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