Anti-Human LPL/LIPD Recombinant Antibody (5D2), APC (HY363137)

Name: Anti-Human LPL/LIPD Recombinant Antibody (5D2), APC
Brand: abinScience
SKU: HY363137
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HY363137
Species reactivity	Bovine
Applications	ELISA, FCM, IF(P), WB
Host species	Mouse
Isotype	IgG2a
Clone ID	5D2
Conjugation	APC
Clonality	Monoclonal
Target	Phospholipase A1, LIPD, Lipoprotein lipase, LPL
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Accession	P06858
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Lipoprotein lipase (LPL/LIPD) is a ~53 kDa protein. Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. 1. Lutz, EP. et al. (2001) The Journal of clinical investigation 107, 1183-92. PMID: 11342582 2. Pingitore, P. et al. (2016) Journal of clinical lipidology 10, 816-823. PMID: 27578112 3. Weinstock, PH. et al. (1995) The Journal of clinical investigation 96, 2555-68. PMID: 8675619 4. McCoy, MG. et al. (2002) Journal of lipid research 43, 921-9. PMID: 12032167 5. Dugi, KA. et al. (1995) The Journal of biological chemistry 270, 25396-401. PMID: 7592706 6. Goulbourne, CN. et al. (2014) Cell metabolism 19, 849-60. PMID: 24726386 7. Allan, CM. et al. (2017) Journal of lipid research 58, 216-225. PMID: 27811232
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human LPL/LIPD Recombinant Antibody (5D2), APC.pdf

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Anti-Human LPL/LIPD Recombinant Antibody (5D2), APC (HY363137)

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