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Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773) (HV777107)

Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)
Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)
Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)
Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)
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Vista general
Número de catálogoHV777107
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA0773
Objetivo Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q8TF66
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Leucine-rich repeat-containing protein 15 (LRRC15/LIB) is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells.

1. Song, J. et al. (2022) PLoS biology 20, e3001805. PMID: 36228039
2. Shilts, J. et al. (2023) PLoS biology 21, e3001959. PMID: 36735681
3. Loo, L. et al. (2023) PLoS biology 21, e3001967. PMID: 36757924
Nota For research use only.
Imágenes
  • Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)

    SDS-PAGE

    SDS-PAGE for Anti-Human LRRC15/LIB Antibody (SAA0773)

  • Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)

    Flow Cytometry

    Flow-cytometry using anti-human LRRC15 antibody.LRRC15 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human LRRC15 antibody monoclonal antibody (Catalog # HV777107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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