

| Numéro de catalogue | HF686137 |
|---|---|
| Reactivité des espèces | Human |
| Applications | ELISA, FCM |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG2a, kappa |
| ID de clone | SAA0416 |
| Conjugaison | APC |
| Cible | TNF-beta, TNFSF1, Tumor necrosis factor ligand superfamily member 1, LTA, Lymphotoxin-alpha, LT-alpha, TNFB |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC |
| Numéro d'accès | P01374 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Lymphotoxin-alpha (LTA/TNF-beta) is a ~22 kDa protein. Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. 1. Mauri, DN. et al. (1998) Immunity 8, 21-30. PMID: 9462508 2. Sudhamsu, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19896-901. PMID: 24248355 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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