Anti-Human Lymphotoxin-alpha/TNF-beta Reference Antibody (Pateclizumab, RUO) (HF686016)

Name: Anti-Human Lymphotoxin-alpha/TNF-beta Reference Antibody (Pateclizumab, RUO)
Brand: abinScience
SKU: HF686016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HF686016
Description	Research Grade Pateclizumab (HF686016) is a humanized monoclonal antibody detecting TNF-beta in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Species	Human
Clonality	Monoclonal
Target	TNF-beta, TNFSF1, Tumor necrosis factor ligand superfamily member 1, LTA, Lymphotoxin-alpha, LT-alpha, TNFB
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01374
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	MLTA3698A, PRO283698, RG7416, 1202526-59-7
Background	Lymphotoxin-alpha (TNF-beta,TNFSF1,Tumor necrosis factor ligand superfamily member 1,LTA,Lymphotoxin-alpha,LT-alpha,TNFB) is a ~22 kDa protein. Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. 1. Mauri, DN. et al. (1998) Immunity 8, 21-30. PMID: 9462508 2. Sudhamsu, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19896-901. PMID: 24248355
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Pateclizumab.

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Datasheet

Anti-Human Lymphotoxin-alpha/TNF-beta Reference Antibody (Pateclizumab, RUO).pdf

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Anti-Human Lymphotoxin-alpha/TNF-beta Reference Antibody (Pateclizumab, RUO) (HF686016)

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