Anti-Human LTBP1 Recombinant Antibody (SAA1797) (HC410013)

Name: Anti-Human LTBP1 Recombinant Antibody (SAA1797)
Brand: abinScience
SKU: HC410013
Price: 196 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC410013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1797

Objetivo

Transforming growth factor beta-1-binding protein 1, Latent-transforming growth factor beta-binding protein 1, LTBP-1, LTBP1, TGF-beta1-BP-1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q14766

RRID

Anti-Human LTBP1 Antibody (SAA1797) (abinScience Cat# HC410013, RRID:AB_3727559)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Latent-transforming growth factor beta-binding protein 1 (LTBP1) is a ~186 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.

1. Miyazono, K. et al. (1991) The EMBO journal 10, 1091-101. PMID: 2022183

2. Saharinen, J. et al. (1996) The EMBO journal 15, 245-53. PMID: 8617200

3. Gleizes, PE. et al. (1996) The Journal of biological chemistry 271, 29891-6. PMID: 8939931

4. Annes, JP. et al. (2004) The Journal of cell biology 165, 723-34. PMID: 15184403

5. Wang, R. et al. (2012) Molecular biology of the cell 23, 1129-39. PMID: 22278742

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human LTBP1 Antibody (SAA1797)

Referencias

Datasheet

Anti-Human LTBP1 Recombinant Antibody (SAA1797).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo