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Anti-Human LTK Polyclonal Antibody
Anti-Human LTK Polyclonal Antibody
Цена(USD): --
Спецификация:
  • 50ug
  • 100ug
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHB966014
Описание
Anti-Human LTK Polyclonal Antibody (HB966014) is a rabbit polyclonal antibody detecting LTK. Suitable for Human.
Реактивность видовHuman
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Human LTK (Ser67-Asn380).
Цель EC:2.7.10.1, LTK, Leukocyte tyrosine kinase receptor, Protein tyrosine kinase 1, TYK1
Уровень эндотоксинов Please contact with the lab for this information.
Очистка Purified by antigen affinity column.
Номер доступа P29376
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Фон

Leukocyte tyrosine kinase receptor (LTK) is a ~91 kDa protein. Receptor with a tyrosine-protein kinase activity. Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. The exact function of this protein is not known; studies with chimeric proteins demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival.

1. Honda, H. et al. (1999) Oncogene 18, 3821-30. PMID: 10445845
2. Farhan, H. et al. (2010) The Journal of cell biology 189, 997-1011. PMID: 20548102
3. Reshetnyak, AV. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 8340-8345. PMID: 30061385
4. De Munck, S. et al. (2021) Nature 600, 143-147. PMID: 34646012
5. Yamada, S. et al. (2008) Neuroreport 19, 1733-8. PMID: 18849880
6. Ueno, H. et al. (1997) Oncogene 14, 3067-72. PMID: 9223670
Примечание For research use only
Изображения
  • Anti-Human LTK Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-LTK polyclonal antibody at 1ug/mL on various samples.
    Lane 1: K562 cell lysate
    Lane 2: HL-60 cell lysate
    Lane 3: THP-1 cell lysate

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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