Anti-Human MAG Recombinant Antibody (SAA0779), APC (HB948137)

Name: Anti-Human MAG Recombinant Antibody (SAA0779), APC
Brand: abinScience
SKU: HB948137
Price: 290 USD
Availability: InStock

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Обзор

Каталожный номер	HB948137
Реактивность видов	Human
Применения	ELISA, FCM
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	SAA0779
Конъюгация	APC
Цель	Myelin-associated glycoprotein, MAG, Siglec-4a, GMA
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Номер доступа	P20916
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Myelin-associated glycoprotein (MAG) is a ~69 kDa protein. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane. Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides.
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human MAG Recombinant Antibody (SAA0779), APC.pdf

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