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Anti-Human MAG/Siglec-4a Recombinant Antibody (SAA0779) (HB948107)

Anti-Human MAG/Siglec-4a Recombinant Antibody (SAA0779)
Anti-Human MAG/Siglec-4a Recombinant Antibody (SAA0779)
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Especificación:
  • 50ug
  • 100ug
Número:
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  • Vista general

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  • Datasheet

  • SDS

Vista general
Número de catálogoHB948107
Reactividad de especiesHuman
AplicacionesBlocking, ELISA, FCM
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonSAA0779
Objetivo Myelin-associated glycoprotein, MAG, Siglec-4a, GMA
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P20916
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Myelin-associated glycoprotein (MAG) is a ~69 kDa protein. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane. Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides.

Nota For research use only.
Imágenes
  • Anti-Human MAG/Siglec-4a Recombinant Antibody (SAA0779)

    SDS-PAGE

    SDS-PAGE for Anti-Human MAG Antibody (SAA0779)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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