

| Numéro de catalogue | HA153014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MCIDAS Polyclonal Antibody (HA153014) is a rabbit polyclonal antibody detecting McIdas protein in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MCIDAS (Thr314-Ser385). | ||||||||
| Cible | Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | D6RGH6 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Multicilin (MCIDAS) is a ~41 kDa protein. Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. 1. Boon, M. et al. (2014) Nature communications 5, 4418. PMID: 25048963 2. Pefani, DE. et al. (2011) The Journal of biological chemistry 286, 23234-46. PMID: 21543332 3. Caillat, C. et al. (2013) The Journal of biological chemistry 288, 31624-34. PMID: 24064211 | ||||||||
| Note | For research use only. |
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