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| カタログ番号 | HA153014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human MCIDAS Polyclonal Antibody (HA153014) is a rabbit polyclonal antibody detecting McIdas protein in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MCIDAS (Thr314-Ser385). | ||||||||
| ターゲット | Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | D6RGH6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Multicilin (MCIDAS) is a ~41 kDa protein. Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. 1. Boon, M. et al. (2014) Nature communications 5, 4418. PMID: 25048963 2. Pefani, DE. et al. (2011) The Journal of biological chemistry 286, 23234-46. PMID: 21543332 3. Caillat, C. et al. (2013) The Journal of biological chemistry 288, 31624-34. PMID: 24064211 | ||||||||
| 注意事項 | For research use only. |
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