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Anti-Human MCM3AP Polyclonal Antibody (HD528014)

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Vista general
Número de catálogoHD528014
Descripción
Anti-Human MCM3AP Polyclonal Antibody (HD528014) is a rabbit polyclonal antibody detecting MCM3AP. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human MCM3AP (Thr602-Gly969).
Objetivo 80 kDa MCM3-associated protein, EC:2.3.1.-, EC:2.3.1.48, GANP, Germinal-center associated nuclear protein, KIAA0572, MAP80, MCM3 acetylating protein, MCM3 acetyltransferase, MCM3AP
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O60318
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Germinal-center associated nuclear protein (MCM3AP) is a ~218 kDa protein. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations.

1. Wickramasinghe, VO. et al. (2010) Current biology : CB 20, 25-31. PMID: 20005110
2. Okamoto, N. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 471-84. PMID: 20384790
3. Jani, D. et al. (2012) Nucleic acids research 40, 4562-73. PMID: 22307388
4. Umlauf, D. et al. (2013) Journal of cell science 126, 2656-67. PMID: 23591820
5. Singh, SK. et al. (2013) Nature communications 4, 1830. PMID: 23652018
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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