Anti-Human MDK/Midkine Recombinant Antibody (SAA1776) (HB964013)

Name: Anti-Human MDK/Midkine Recombinant Antibody (SAA1776)
Brand: abinScience
SKU: HB964013
Price: 110 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB964013

Descripción

Anti-Human MDK/Midkine Recombinant Antibody (SAA1776) (HB964013) is a mouse monoclonal antibody detecting MDK/Midkine in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1776

Objetivo

Amphiregulin-associated protein, Midgestation and kidney protein, NEGF2, MDK, ARAP, MK1, Neurite outgrowth-promoting factor 2, MK, Midkine, Neurite outgrowth-promoting protein

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P21741

RRID

Anti-Human MDK/Midkine Antibody (SAA1776) (abinScience Cat# HB964013, RRID:AB_3727538)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

1. Maeda, N. et al. (1999) The Journal of biological chemistry 274, 12474-9. PMID: 10212223

2. Muramatsu, H. et al. (2000) Biochemical and biophysical research communications 270, 936-41. PMID: 10772929

3. Kurosawa, N. et al. (2001) Glycoconjugate journal 18, 499-507. PMID: 12084985

4. Stoica, GE. et al. (2002) The Journal of biological chemistry 277, 35990-8. PMID: 12122009

5. Sakaguchi, N. et al. (2003) Neuroscience research 45, 219-24. PMID: 12573468

6. Muramatsu, H. et al. (2004) Journal of cell science 117, 5405-15. PMID: 15466886

7. Huang, Y. et al. (2008) Cell cycle (Georgetown, Tex.) 7, 1613-22. PMID: 18469519

8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438

9. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378

Nota

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human MDK/Midkine Antibody (SAA1776)

Referencias

Datasheet

Anti-Human MDK/Midkine Recombinant Antibody (SAA1776).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo