Anti-Human MDK/Midkine Recombinant Antibody (SAA1776) (HB964013)

Name: Anti-Human MDK/Midkine Recombinant Antibody (SAA1776)
Brand: abinScience
SKU: HB964013
Price: 110 USD
Availability: InStock

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1mg

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB964013

Description

Anti-Human MDK/Midkine Recombinant Antibody (SAA1776) (HB964013) is a mouse monoclonal antibody detecting MDK/Midkine in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1776

Cible

Amphiregulin-associated protein, Midgestation and kidney protein, NEGF2, MDK, ARAP, MK1, Neurite outgrowth-promoting factor 2, MK, Midkine, Neurite outgrowth-promoting protein

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P21741

RRID

Anti-Human MDK/Midkine Antibody (SAA1776) (abinScience Cat# HB964013, RRID:AB_3727538)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

1. Maeda, N. et al. (1999) The Journal of biological chemistry 274, 12474-9. PMID: 10212223

2. Muramatsu, H. et al. (2000) Biochemical and biophysical research communications 270, 936-41. PMID: 10772929

3. Kurosawa, N. et al. (2001) Glycoconjugate journal 18, 499-507. PMID: 12084985

4. Stoica, GE. et al. (2002) The Journal of biological chemistry 277, 35990-8. PMID: 12122009

5. Sakaguchi, N. et al. (2003) Neuroscience research 45, 219-24. PMID: 12573468

6. Muramatsu, H. et al. (2004) Journal of cell science 117, 5405-15. PMID: 15466886

7. Huang, Y. et al. (2008) Cell cycle (Georgetown, Tex.) 7, 1613-22. PMID: 18469519

8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438

9. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378

Note

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

Images

SDS-PAGE

SDS-PAGE for Anti-Human MDK/Midkine Antibody (SAA1776)

Reférences

Fiche technique

Anti-Human MDK/Midkine Recombinant Antibody (SAA1776).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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