Anti-Human MDK Polyclonal Antibody (HB964014)

Name: Anti-Human MDK Polyclonal Antibody
Brand: abinScience
SKU: HB964014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HB964014

Описание

Anti-Human MDK Polyclonal Antibody (HB964014) is a rabbit polyclonal antibody detecting MDK. Suitable for Rat and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human MDK (Val21-Asp143).

Цель

ARAP, Amphiregulin-associated protein, MDK, MK, MK1, Midgestation and kidney protein, Midkine, NEGF2, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P21741

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Фон

Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

1. Maeda, N. et al. (1999) The Journal of biological chemistry 274, 12474-9. PMID: 10212223

2. Muramatsu, H. et al. (2000) Biochemical and biophysical research communications 270, 936-41. PMID: 10772929

3. Kurosawa, N. et al. (2001) Glycoconjugate journal 18, 499-507. PMID: 12084985

4. Stoica, GE. et al. (2002) The Journal of biological chemistry 277, 35990-8. PMID: 12122009

5. Sakaguchi, N. et al. (2003) Neuroscience research 45, 219-24. PMID: 12573468

6. Muramatsu, H. et al. (2004) Journal of cell science 117, 5405-15. PMID: 15466886

7. Huang, Y. et al. (2008) Cell cycle (Georgetown, Tex.) 7, 1613-22. PMID: 18469519

8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438

9. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Human MDK Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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