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| カタログ番号 | HP101014 | ||||||||
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| 説明 |
Anti-Human MED15 Polyclonal Antibody (HP101014) is a rabbit polyclonal antibody detecting MED15 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MED15 (Ser676-Ala788). | ||||||||
| ターゲット | MED15, Activator-recruited cofactor 105 kDa component, TPA-inducible gene 1 protein, ARC105, TIG1, Mediator complex subunit 15, TIG-1, Positive cofactor 2 glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, Mediator of RNA polymerase II transcription subunit 15, PCQAP, TNRC7, Trinucleotide repeat-containing gene 7 protein, CTG7A, CTG repeat protein 7a | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q96RN5 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Mediator of RNA polymerase II transcription subunit 15 (MED15) is a ~86 kDa protein. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway. | ||||||||
| 注意事項 | For research use only. |
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