

| Número de catálogo | HY196013 | ||||||
|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human HGFR/c-MET Recombinant Antibody (SAA0765) (HY196013) is a human monoclonal antibody detecting HGFR/c-MET in ELISA, WB. Suitable for Human.
Highlights
|
||||||
| Reactividad de especies | Human | ||||||
| Aplicaciones | ELISA, WB | ||||||
| Especie huésped | Human | ||||||
| Clonalidad | Monoclonal | ||||||
| Isotipo | IgG1 | ||||||
| ID de clon | SAA0765 | ||||||
| Objetivo | Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET, RCCP2 | ||||||
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. | ||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||||
| Número de acceso | P08581 | ||||||
| Forma | Liquid | ||||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||
| Información de uso del producto |
| ||||||
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Fondo | Hepatocyte growth factor receptor (MET/HGFR) is a ~155 kDa protein. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. MET is the therapeutic target of amivantamab (Rybrevant). | ||||||
| Nota | For research use only. | ||||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for Anti-Human MET/c-Met/HGFR Antibody (SAA0765).




Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]


Acceso rápido
Contáctenos
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский