Anti-Human MMP3 Recombinant Antibody (SAA1516) (HY526013)

Name: Anti-Human MMP3 Recombinant Antibody (SAA1516)
Brand: abinScience
SKU: HY526013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY526013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1516

Objetivo

SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P08254

RRID

Anti-Human MMP3 Antibody (SAA1516) (abinScience Cat# HY526013, RRID:AB_3727277)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Stromelysin-1 (MMP3) is a ~53 kDa protein. Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. Also acts intracellularly. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage.

1. Arza, B. et al. (2000) European journal of biochemistry 267, 6378-84. PMID: 11029580

2. Ogata, Y. et al. (1992) The Journal of biological chemistry 267, 3581-4. PMID: 1371271

3. Nagase, H. et al. (1990) Biochemistry 29, 5783-9. PMID: 2383557

4. Shin, EJ. et al. (2012) Neurochemistry international 60, 249-56. PMID: 22265821

5. Choi, DH. et al. (2011) The Journal of biological chemistry 286, 14168-77. PMID: 21330369

6. Feng, T. et al. (2022) Antiviral research 206, 105388. PMID: 35940311

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human MMP3 Antibody (SAA1516)

Referencias

Datasheet

Anti-Human MMP3 Recombinant Antibody (SAA1516).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo