Anti-Human MMP3 Recombinant Antibody (SAA1516) (HY526013)

Name: Anti-Human MMP3 Recombinant Antibody (SAA1516)
Brand: abinScience
SKU: HY526013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HY526013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1516

Cible

SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P08254

RRID

Anti-Human MMP3 Antibody (SAA1516) (abinScience Cat# HY526013, RRID:AB_3727277)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Stromelysin-1 (MMP3) is a ~53 kDa protein. Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. Also acts intracellularly. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage.

1. Arza, B. et al. (2000) European journal of biochemistry 267, 6378-84. PMID: 11029580

2. Ogata, Y. et al. (1992) The Journal of biological chemistry 267, 3581-4. PMID: 1371271

3. Nagase, H. et al. (1990) Biochemistry 29, 5783-9. PMID: 2383557

4. Shin, EJ. et al. (2012) Neurochemistry international 60, 249-56. PMID: 22265821

5. Choi, DH. et al. (2011) The Journal of biological chemistry 286, 14168-77. PMID: 21330369

6. Feng, T. et al. (2022) Antiviral research 206, 105388. PMID: 35940311

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MMP3 Antibody (SAA1516)

Reférences

Fiche technique

Anti-Human MMP3 Recombinant Antibody (SAA1516).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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