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Anti-Human MMP-9 Recombinant Antibody (SAA0116), APC (HB945137)

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Aperçu
Numéro de catalogueHB945137
Reactivité des espècesHuman, Rat
ApplicationsELISA, FCM
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4, kappa
ID de cloneSAA0116
ConjugaisonAPC
Cible Matrix metalloproteinase-9, CLG4B, GELB, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, MMP9, MMP-9
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), APC
Numéro d'accès P14780
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Matrix metalloproteinase-9 (MMP9) is a ~78 kDa protein. Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments.

1. Takino, T. et al. (2003) Oncogene 22, 4617-26. PMID: 12879005
2. Tschesche, H. et al. (1992) Matrix (Stuttgart, Germany). Supplement 1, 245-55. PMID: 1480034
3. Wilhelm, SM. et al. (1989) The Journal of biological chemistry 264, 17213-21. PMID: 2551898
4. Jeon, S. et al. (2020) Circulation 142, 1736-1751. PMID: 32883094
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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