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Anti-Human MMP-9 Recombinant Antibody (SAA0116) (HB945107)

Anti-Human MMP-9 Recombinant Antibody (SAA0116)
Anti-Human MMP-9 Recombinant Antibody (SAA0116)
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概要
カタログ番号HB945107
種反応性Human, Rat
アプリケーションELISA, FCM, IHC
宿主種Human
クローン性Monoclonal
アイソタイプIgG4, kappa
クローンIDSAA0116
テスト済みアプリケーション FCM
ターゲット Matrix metalloproteinase-9, CLG4B, GELB, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, MMP9, MMP-9
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P14780
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Matrix metalloproteinase-9 (MMP9) is a ~78 kDa protein. Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments.

1. Takino, T. et al. (2003) Oncogene 22, 4617-26. PMID: 12879005
2. Tschesche, H. et al. (1992) Matrix (Stuttgart, Germany). Supplement 1, 245-55. PMID: 1480034
3. Wilhelm, SM. et al. (1989) The Journal of biological chemistry 264, 17213-21. PMID: 2551898
4. Jeon, S. et al. (2020) Circulation 142, 1736-1751. PMID: 32883094
注意事項 For research use only.
イメージ
  • Anti-Human MMP-9 Recombinant Antibody (SAA0116)

    Flow Cytometry

    Flow-cytometry using anti-human MMP9 antibody.MMP9 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human MMP9 antibody monoclonal antibody (Catalog # HB945107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
Formula
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