

| カタログ番号 | HP852025 |
|---|---|
| 説明 |
Anti-Human MOSPD2 Monoclonal Antibody (1A129) [1A129] (HP852025) is a mouse monoclonal antibody detecting MOSPD2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, IHC, WB |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1 |
| クローンID | 1A129 |
| 免疫原 | Mammalian cells - derived recombinant Human MOSPD2 (Met1-Asp469). |
| ターゲット | Motile sperm domain-containing protein 2, MOSPD2, |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q8NHP6 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Motile sperm domain-containing protein 2 (MOSPD2) is a ~59 kDa protein. Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. Promotes migration of primary monocytes and neutrophils, in response to various chemokines. 1. Di Mattia, T. et al. (2018) EMBO reports 19. PMID: 29858488 2. Di Mattia, T. et al. (2020) The EMBO journal 39, e104369. PMID: 33124732 3. Zouiouich, M. et al. (2022) The Journal of cell biology 221. PMID: 35389430 4. Mendel, I. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2125-2132. PMID: 28137892 |
| 注意事項 | For research use only. |

SDS-PAGE for Anti-Human MOSPD2 Monoclonal Antibody (1A129)


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