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Human MOSPD2 Recombinant Protein (N-His) (HP852022)

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Overview
Catalog No.HP852022
Description
Recombinant Human MOSPD2 Protein, N-His (HP852022) expressed in E. coli, spanning Met1-Thr251. Purity: >90% by SDS-PAGE.
Highlights
  • His-Tagged — N-terminal 6×His tag for IMAC purification.
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionQ8NHP6
Protein lengthMet1-Thr251
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 32.20 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesMOSPD2, Motile sperm domain-containing protein 2
Background

Motile sperm domain-containing protein 2 is a ~59 kDa protein. Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. Promotes migration of primary monocytes and neutrophils, in response to various chemokines.

1. Di Mattia, T. et al. (2018) EMBO reports 19. PMID: 29858488
2. Di Mattia, T. et al. (2020) The EMBO journal 39, e104369. PMID: 33124732
3. Zouiouich, M. et al. (2022) The Journal of cell biology 221. PMID: 35389430
4. Mendel, I. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2125-2132. PMID: 28137892
Note For research use only
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Formula
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Formula
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