Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12) (HV344043)

Name: Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12)
Brand: abinScience
SKU: HV344043
Price: 126 USD
Availability: InStock

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Цена(USD):

Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HV344043

Реактивность видов

Human, Mouse

Применения

ELISA, Neutralization

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a-kappa

ID клона

14D12

Цель

ANGPTL4

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q9BY76

RRID

Anti-Human/Mouse ANGPTL4 Antibody (14D12) (abinScience Cat# HV344043, RRID:AB_3729819)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Доставка

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Альтернативные названия

Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP, ANGPTL4 N-terminal chain, ANGPTL4 C-terminal chain, ANGPTL4

Фон

Angiopoietin-related protein 4 (ANGPTL4) is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis.

1. Yin, W. et al. (2009) The Journal of biological chemistry 284, 13213-22. PMID: 19270337

2. Lei, X. et al. (2011) The Journal of biological chemistry 286, 15747-56. PMID: 21398697

3. Mysling, S. et al. (2016) eLife 5. PMID: 27929370

4. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144

5. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458

6. Cazes, A. et al. (2006) Circulation research 99, 1207-15. PMID: 17068295

Примечание

For research use only.

Isotype Control

Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)

Изображения