Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934) (HF729013)

Name: Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934)
Brand: abinScience
SKU: HF729013
Price: 110 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF729013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1934

Cible

G6B, G6B-B, Protein G6b, MPIG6B, C6orf25, Megakaryocyte and platelet inhibitory receptor G6b

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O95866

RRID

Anti-Human MPIG6B/G6b Antibody (SAA1934) (abinScience Cat# HF729013, RRID:AB_3727698)
_x005F_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Megakaryocyte and platelet inhibitory receptor G6b (MPIG6B) is a ~26 kDa protein. Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner.

1. Gevaert, K. et al. (2003) Nature biotechnology 21, 566-9. PMID: 12665801

2. Newland, SA. et al. (2007) Blood 109, 4806-9. PMID: 17311996

3. Melhem, M. et al. (2017) European journal of haematology 98, 218-227. PMID: 27743390

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human MPIG6B/G6b Antibody (SAA1934)

Reférences

Fiche technique

Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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