

| Каталожный номер | HF729013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a, kappa | ||||
| ID клона | SAA1934 | ||||
| Цель | G6B, G6B-B, Protein G6b, MPIG6B, C6orf25, Megakaryocyte and platelet inhibitory receptor G6b | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | O95866 | ||||
| RRID | Anti-Human MPIG6B/G6b Antibody (SAA1934) (abinScience Cat# HF729013, RRID:AB_3727698) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Megakaryocyte and platelet inhibitory receptor G6b (MPIG6B) is a ~26 kDa protein. Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner. 1. Gevaert, K. et al. (2003) Nature biotechnology 21, 566-9. PMID: 12665801 2. Newland, SA. et al. (2007) Blood 109, 4806-9. PMID: 17311996 3. Melhem, M. et al. (2017) European journal of haematology 98, 218-227. PMID: 27743390 | ||||
| Примечание | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human MPIG6B/G6b Antibody (SAA1934)
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