Anti-Human MTF2 IP Recombinant Antibody (SAA0253) (HP178013)

Name: Anti-Human MTF2 IP Recombinant Antibody (SAA0253)
Brand: abinScience
SKU: HP178013
Price: 191 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HP178013

Реактивность видов

Human

Применения

ELISA, IF, IP

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a

ID клона

SAA0253

Цель

hPCl2, Metal-response element-binding transcription factor 2, Polycomb-like protein 2, PCL2, MTF2, Metal regulatory transcription factor 2, Metal-response element DNA-binding protein M96

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q9Y483

RRID

Anti-Human MTF2 IP Antibody (SAA0253) (abinScience Cat# HP178013, RRID:AB_3729787)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Metal-response element-binding transcription factor 2 (MTF2) is a ~67 kDa protein. Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally.

1. Musselman, CA. et al. (2012) Nature structural & molecular biology 19, 1266-72. PMID: 23142980

2. Qin, S. et al. (2013) Biochemical and biophysical research communications 430, 547-53. PMID: 23228662

3. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human MTF2 IP Antibody (SAA0253)

Ссылки

Даташит

Anti-Human MTF2 IP Recombinant Antibody (SAA0253).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа