Anti-Human NT-ProBNP Monoclonal Antibody (1A345) (HB840025)

Name: Anti-Human NT-ProBNP Monoclonal Antibody (1A345)
Brand: abinScience
SKU: HB840025
Price: 194 USD
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Número de catálogo	HB840025
Descripción	Anti-Human NT-ProBNP Monoclonal Antibody (1A345) [1A345] (HB840025) is a mouse monoclonal antibody detecting NT-proBNP in CLIA. Suitable for Human.
Reactividad de especies	Human
Aplicaciones	CLIA
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	1A345
Inmunógeno	Human NT-ProBNP Protein.
Objetivo	Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP, NT-proBNP, NT-pro-BNP, NT-proBNP(1-76), proBNP(3-108), NPPB
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P16860
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Natriuretic peptides B (NT-ProBNP) is a ~14 kDa protein. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3. 1. Koller, KJ. et al. (1991) Science (New York, N.Y.) 252, 120-3. PMID: 1672777 2. Heublein, DM. et al. (2007) Hypertension (Dallas, Tex. : 1979) 49, 1114-9. PMID: 17372040 3. Yoshimura, M. et al. (1991) Circulation 84, 1581-8. PMID: 1914098 4. Jensen, KT. et al. (1998) The American journal of physiology 274, F63-72. PMID: 9458824 5. Liang, F. et al. (2007) Journal of the American College of Cardiology 49, 1071-8. PMID: 17349887 6. Ralat, LA. et al. (2011) The Journal of biological chemistry 286, 4670-9. PMID: 21098034 7. Huntley, BK. et al. (2015) Circulation. Heart failure 8, 89-97. PMID: 25339504
Nota	For research use only.