Anti-Human NT-ProBNP Monoclonal Antibody (1A345) (HB840025)

Name: Anti-Human NT-ProBNP Monoclonal Antibody (1A345)
Brand: abinScience
SKU: HB840025
Price: 194 USD
Availability: InStock

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Numéro de catalogue	HB840025
Description	Anti-Human NT-ProBNP Monoclonal Antibody (1A345) [1A345] (HB840025) is a mouse monoclonal antibody detecting NT-proBNP in CLIA. Suitable for Human.
Reactivité des espèces	Human
Applications	CLIA
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG
ID de clone	1A345
Immunogène	Human NT-ProBNP Protein.
Cible	Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP, NT-proBNP, NT-pro-BNP, NT-proBNP(1-76), proBNP(3-108), NPPB
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P16860
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Natriuretic peptides B (NT-ProBNP) is a ~14 kDa protein. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3. 1. Koller, KJ. et al. (1991) Science (New York, N.Y.) 252, 120-3. PMID: 1672777 2. Heublein, DM. et al. (2007) Hypertension (Dallas, Tex. : 1979) 49, 1114-9. PMID: 17372040 3. Yoshimura, M. et al. (1991) Circulation 84, 1581-8. PMID: 1914098 4. Jensen, KT. et al. (1998) The American journal of physiology 274, F63-72. PMID: 9458824 5. Liang, F. et al. (2007) Journal of the American College of Cardiology 49, 1071-8. PMID: 17349887 6. Ralat, LA. et al. (2011) The Journal of biological chemistry 286, 4670-9. PMID: 21098034 7. Huntley, BK. et al. (2015) Circulation. Heart failure 8, 89-97. PMID: 25339504
Note	For research use only.