Anti-Human TrkA Monoclonal Antibody (1A717) (HY107015)

Name: Anti-Human TrkA Monoclonal Antibody (1A717)
Brand: abinScience
SKU: HY107015
Price: 106 USD
Availability: InStock

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Каталожный номер	HY107015
Описание	Anti-Human NTRK1 Monoclonal Antibody (1A717) [1A717] (HY107015) is a mouse monoclonal antibody detecting NTRK1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Реактивность видов	Human
Применения	ELISA, IHC, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG
ID клона	1A717
Иммуноген	E. coli - derived recombinant human NTRK1 (Asp38-Phe378).
Цель	High affinity nerve growth factor receptor, EC:2.7.10.1, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, Trk-A, gp140trk, p140-TrkA, NTRK1
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P04629
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	High affinity nerve growth factor receptor (NTRK1) is a ~87 kDa protein. Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand. Can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. 1. Jing, S. et al. (1992) Neuron 9, 1067-79. PMID: 1281417 2. Tacconelli, A. et al. (2004) Cancer cell 6, 347-60. PMID: 15488758 3. Wehrman, T. et al. (2007) Neuron 53, 25-38. PMID: 17196528 4. Klein, R. et al. (1991) Cell 65, 189-97. PMID: 1849459 5. Hempstead, BL. et al. (1991) Nature 350, 678-83. PMID: 1850821 6. Tong, Q. et al. (2012) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 26, 3811-21. PMID: 22649032 7. Anta, B. et al. (2016) The Journal of biological chemistry 291, 19132-45. PMID: 27445338 8. Barker, PA. et al. (1993) The Journal of biological chemistry 268, 15150-7. PMID: 8325889
Примечание	For research use only.

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Anti-Human TrkA Monoclonal Antibody (1A717).pdf

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Anti-Human TrkA Monoclonal Antibody (1A717) (HY107015)

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