Anti-Human Perforin Recombinant Antibody (SAA0104) (HB886107)

Name: Anti-Human Perforin Recombinant Antibody (SAA0104)
Brand: abinScience
SKU: HB886107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB886107
Reactivité des espèces	Human
Applications	FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	SAA0104
Cible	Cytolysin, Perforin-1, Lymphocyte pore-forming protein, PFP, PRF1, P1
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P14222
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Perforin-1 is a ~61 kDa protein. Pore-forming protein that plays a key role in granzyme-mediated programmed cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by mediating the passage and uptake of cytotoxic granzymes. 1. Praper, T. et al. (2011) The Journal of biological chemistry 286, 2946-55. PMID: 20889983 2. Law, RH. et al. (2010) Nature 468, 447-51. PMID: 21037563 3. Stewart, SE. et al. (2014) The Journal of biological chemistry 289, 9172-81. PMID: 24558045 4. Vergelli, M. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 2756-61. PMID: 9058810 5. Ando, K. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 5283-91. PMID: 9164947 6. Thiery, J. et al. (2010) Blood 115, 1582-93. PMID: 20038786 7. Czystowska, M. et al. (2010) Journal of molecular medicine (Berlin, Germany) 88, 577-88. PMID: 20225066 8. Zhou, Z. et al. (2020) Science (New York, N.Y.) 368. PMID: 32299851
Note	For research use only.

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SDS-PAGE for Anti-Human Perforin Antibody (SAA0104)

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Anti-Human Perforin Recombinant Antibody (SAA0104).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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