Anti-Human PGLYRP1 Recombinant Antibody (SAA1529) (HF951013)

Name: Anti-Human PGLYRP1 Recombinant Antibody (SAA1529)
Brand: abinScience
SKU: HF951013
Price: 191 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF951013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1529

Cible

Peptidoglycan recognition protein 1, PGLYRP, PGRP, Peptidoglycan recognition protein short, TNFSF3L, PGRP-S, PGLYRP1

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O75594

RRID

Anti-Human PGLYRP1 Antibody (SAA1529) (abinScience Cat# HF951013, RRID:AB_3727290)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Peptidoglycan recognition protein 1 (PGLYRP1) is a ~21 kDa protein. Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems. Acts as a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria and thus provides bactericidal activity. Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane. In addition, acts in complex with the Ca(2+)-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement. Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system.

1. Kang, D. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 10078-82. PMID: 9707603

2. Yashin, DV. et al. (2011) The Journal of biological chemistry 286, 10258-64. PMID: 21247889

3. Yashin, DV. et al. (2015) The Journal of biological chemistry 290, 21724-31. PMID: 26183779

4. Dukhanina, EA. et al. (2015) Cell cycle (Georgetown, Tex.) 14, 3635-43. PMID: 26654597

5. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770

6. Sharapova, TN. et al. (2017) Journal of innate immunity 9, 598-608. PMID: 28977785

7. Sharapova, TN. et al. (2017) IUBMB life 69, 971-977. PMID: 29083508

8. Read, CB. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 1417-21. PMID: 25595774

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human PGLYRP1 Antibody (SAA1529)

Reférences

Fiche technique

Anti-Human PGLYRP1 Recombinant Antibody (SAA1529).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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