

| Número de catálogo | HC189014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human PMPCB Polyclonal Antibody (HC189014) is a rabbit polyclonal antibody detecting PMPCB. Suitable for Human, Rat, and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human PMPCB (Arg59-Asp489). | ||||||||
| Objetivo | Beta-MPP, EC:3.4.24.64, MPPB, Mitochondrial-processing peptidase subunit beta, P-52, PMPCB | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O75439 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Mitochondrial-processing peptidase subunit beta (PMPCB) is a ~54 kDa protein. Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis. 1. Vögtle, FN. et al. (2018) American journal of human genetics 102, 557-573. PMID: 29576218 2. Greene, AW. et al. (2012) EMBO reports 13, 378-85. PMID: 22354088 | ||||||||
| Nota | For research use only |
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