Human PMPCB Recombinant Protein (N-His) (HC189012)

Name: Human PMPCB Recombinant Protein (N-His)
Brand: abinScience
SKU: HC189012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC189012
Description	Recombinant Human PMPCB Protein, N-His (HC189012) expressed in E. coli, spanning Arg59-Asp489. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O75439
Protein length	Arg59-Asp489
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	50.43 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Beta-MPP, EC:3.4.24.64, MPPB, Mitochondrial-processing peptidase subunit beta, P-52, PMPCB
Background	Mitochondrial-processing peptidase subunit beta is a ~54 kDa protein. Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis. 1. Vögtle, FN. et al. (2018) American journal of human genetics 102, 557-573. PMID: 29576218 2. Greene, AW. et al. (2012) EMBO reports 13, 378-85. PMID: 22354088
Note	For research use only

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Datasheet

Human PMPCB Recombinant Protein (N-His).pdf

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Human PMPCB Recombinant Protein (N-His) (HC189012)

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