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| カタログ番号 | HA024013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1888 | ||||
| ターゲット | UPA, Proline-rich acidic protein 1, Epididymis tissue protein Li 178, Uterine-specific proline-rich acidic protein, PRAP1 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q96NZ9 | ||||
| RRID | Anti-Human PRAP1/uPA Antibody (SAA1888) (abinScience Cat# HA024013, RRID:AB_3727652) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Proline-rich acidic protein 1 (PRAP1/uPA) is a ~17 kDa protein. Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas. 1. Zhang, J. et al. (2003) Cancer research 63, 6658-65. PMID: 14583459 2. Huang, BH. et al. (2012) Cell death & disease 3, e442. PMID: 23235459 3. Sze, KM. et al. (2014) The Journal of pathology 233, 51-60. PMID: 24374861 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human PRAP1/uPA Antibody (SAA1888)
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